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Divinity Original Sin 2: How to Make (& Use) Runes

Sep 2nd 2025, 3:59 am
Posted by olivemilto
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**Divinity: Original Sin 2 ** is filled with a wealth of secrets and strategies. With each regular update, Larian Studios has been adding in brand new abilities and features . This can bring about interesting ways of creating a powerful party , regardless if it is your first-time experience or a re-playthrough.


Related: How to Get Four Relics Armor in Divinity Original Sin 2


As you explore Rivellon you may come across weapons and armor that have slots. These can be imbued with runes that can grant damage, elemental resistance, combat bonuses, and more. It is better to use rune slots as a supplement to strengthen your current build, rather than making a build revolving around runes. Still, if you like a piece of equipment you can always refurbish it into your most outstanding gear .


Crafting Runes in Divinity: Original Sin 2



Runes can be found throughout your adventure, either as treasure or from merchants. However, it can take time to gather up a collection this way. Instead, consider crafting some runes yourself. The supplies can be found all throughout Rivellon. Additionally, if you have access to the Lady Vengeance you can ask Han to fetch your items. As with most crafting, you may have to separate items into singles to avoid combination errors.


Small Rune Creation




  • Masterwork: Livewood Log, Wine, Pixie Dust




  • Flame: Oil, Wood, Pixie Dust




  • Frost: Water, Metal, Pixie Dust




  • Rock: Beer, Rock, Pixie Dust




  • Thunder: Water, Gold, Pixie Dust




  • Venom: Bone, Poison, Pixie Dust




Upgrading Rune Size


Bigger runes will have increased bonuses, making it worthwhile to increase their size.




  • Medium: Two of the same Small runes, Pixie Dust




  • Large: Two of Read the Full Post same Medium runes, Pixie Dust




  • Giant: Two of the same Large runes, Superior Pixie Dust




Pixie Dust Ingredients




  • Stardust: Stardust Herb, Mortar and Pestle




  • Bonedust: Bone, Mortar, and Pestle




  • Superior Stardust: Superior Stardust Herb, Mortar and Pestle




  • Pixie Dust: Stardust, Bonedust




  • Superior Pixie Dust: Superior Stardust, Bonedust




Rune Frames


Frames can be added to a rune to give it even more bonuses. However, once a rune is placed in a frame it can never be removed. This means aim to only place Large or Giant size runes into a frame. Mystical Frames will grant mostly a +1 increase to combat abilities; the exception being Masterwork runes that instead give +3 to secondary attributes like Memory or Wits. Frames of Power instead give boosts to direct damage attributes, based on rune size. Small runes gain +1, Medium and Large +2, and Giant +3.


Keep in mind that these new bonuses are in addition to the base rune, and might not always mesh well. For example, you might not need both a boost to Geomancer and Vitality in your build.


Rune Bonuses in Divinity: Original Sin 2



Runes grant different benefits depending on what item they are slotted into a weapon, armor, or amulet.

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